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2. erythropoiesis:

  • due to a breakdown of megakaryocytes
  • is increased by low arterial PO2 (hypoxia)
  • is an alternative term for anaemia
  • is regulated by erythropoietin released from the spleen
  • is regulated by erythropoietin released from the liver

3. human blood:

  • normally has a pH range of 7.0-7.1
  • is composed of about 40-45% cells, with the remainder plasma
  • normally has a K conc between 20-25mmol/L
  • contains nucleated RBCs
  • volume is about 10L

4. the heart:

  • is tolerant to a lack of blood flow for several mins
  • lacks a pacemaker system
  • ejects about 5L/min of blood in a typical resting adult
  • is composed of skeletal muscle
  • is supplied by somatic motor nerves

5. plasma proteins:

  • include immunoglobulins and albumin
  • readily cross the capillary wall
  • are synthesised in the spleen
  • are important carriers of o2 and co2
  • are responsible for the red colour of blood

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