Unit 2- Key area 2.7

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Atherosclerosis

-Fatty accumulation of substances, mainly of cholesterol, fibrous material and calcium salts, forming an atheroma beneath the endothelium

-The Atheroma grows and makes the artery grow and lose its elascity

-The lumen of the artery becomes narrrowed and restricts blood flow- increasing blood pressure

Thrombosis

-If an atheroma ruptures, the damage to the endothelium of the artery causes the release of clotting factors 

-The enzyme

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