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2. Amide

  • RCONHR'
  • RCOHNHR'
  • RNH3

3. Amide to nitrile

  • P4O10, heat
  • P5O10

4. acyl chlroide to amide

  • NH3 or R-NH2, heat
  • NH3 or R-NH2, r.t.p
  • conc. NH3, r.t.p

5. Nitrile to CA

  • dilute acid, then H2O, heat under reflux
  • conc. acid,then H2O, heat under reflux
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