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2. Nitrile to Amine

  • LiAlH4, dry ether, heat under reflux
  • Acid, heat under reflux

3. carboxylic acid to acyl chloride

  • PCl5, r.t.p
  • HCl, r.t.p

4. Amine to salt

  • acid
  • alkali

5. acyl chlroide to amide

  • NH3 or R-NH2, heat
  • NH3 or R-NH2, r.t.p
  • conc. NH3, r.t.p

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