Module 2.5 - Biological membranes

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fluid mosaic model
theory of cell membrane structure - proteins embedded in a phospholipid bilayer
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glycolipid
lipid/phospholipid with a chain of carbohydrate molecules attached
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glycoprotein
protein with a chain of carbohydrate molecules attached
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plasma membrane functions
partially permeable. separates cell contents from surroundings. regulates transport of materials into/out of cell. has antigens (immune system recognises cell as 'self'). contains receptors for chemical signals - site for cell signalling
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phospholipid molecules' role in the plasma membrane
hydrophilic heads in contact with watery exterior/interior (cytoplasm) and hydrophobic tails in centre of membrane. lipids can swap places, giving fluidity.
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integral proteins
span the whole lipid bilayer, e.g. carrier/channel proteins
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peripheral proteins
don't span the whole lipid bilayer
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role of cholesterol in the plasma membrane
molecules fit between phospholipids and bind to tails so they pack closely together. makes membrane more rigid - stability
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glycocalyx
formed from carbohydrate chains attached to proteins or lipids in the membrane
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carrier proteins
change their shape to carry specific molecules across the membrane
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protein channels
have pores to allow specific ions to pass through
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diffusion
movement of molecules from an area of high to low concentration of that molecule down their concentration gradient. passive process
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facilitated diffusion
movement of molecules from an area of high to low concentration of that molecule across a PPM via protein channels or carriers. passive process
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aquaporins
specific water channel proteins found in membranes where a high rate of water movement is required, so water doesn't have to cross a lipid environment
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how is the concentration gradient maintained?
molecules enter cells, then pass into organelles and are used in metabolic reactions.
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5 factors affecting rate of simple diffusion
temperature, diffusion distance, surface area, size of diffusing molecule, concentration gradient
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how does temperature affect rate of simple diffusion?
as temperature increases, molecules have more kinetic energy, so rate of diffusion increases.
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how does diffusion distance affect rate of simple diffusion?
the thicker the membrane to diffuse across, the slower the rate of diffusion
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how does surface area affect rate of simple diffusion?
more diffusion can take place across a larger surface area
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how does size of diffusion molecule affect rate of simple diffusion?
smaller ions/molecules diffuse quicker than larger ones
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how does concentration gradient affect rate of simple diffusion?
the steeper the gradient, the faster the diffusion down the concentration gradient
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osmosis
diffusion of water molecules down their water potential gradient, from an area of high to low water potential, across a PPM
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water potential
measure of the tendency of water molecules to diffuse from one area to another
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highest possible water potential
0kPa - pure water. lower water potential has a negative value
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cytolysis (/haemolysis)
animal cells swelling and bursting due to many water molecules entering - plasma membrane breaks
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turgidity
plant cell swells and pushes against the cell wall, which prevents further swelling and potential bursting
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crenation
animal cells shrivelling due to many water molecules moving out of the cell
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plasmolysis
plant cell's cytoplasm shrinks and membrane pulls away from the cell wall.
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active transport
movement of substances against their concentration gradient across a cell membrane, using ATP and carrier proteins
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endocytosis
bulk transport of molecules, too large to pass through a cell membrane even via channel or carrier proteins, into a cell
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exocytosis
bulk transport of molecules, too large to pass through a cell membrane even via channel or carrier proteins, out of a cell
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phagocytosis
solid matter ingested by endocytosis
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pinocytosis
liquid matter ingested by endocytosis
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effect of solvents on phospholipids
organic solvents damage cell membranes as they dissolve lipids
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Other cards in this set

Card 2

Front

lipid/phospholipid with a chain of carbohydrate molecules attached

Back

glycolipid

Card 3

Front

protein with a chain of carbohydrate molecules attached

Back

Preview of the back of card 3

Card 4

Front

partially permeable. separates cell contents from surroundings. regulates transport of materials into/out of cell. has antigens (immune system recognises cell as 'self'). contains receptors for chemical signals - site for cell signalling

Back

Preview of the back of card 4

Card 5

Front

hydrophilic heads in contact with watery exterior/interior (cytoplasm) and hydrophobic tails in centre of membrane. lipids can swap places, giving fluidity.

Back

Preview of the back of card 5
View more cards

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