gene expression

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  • Created by: Jess
  • Created on: 16-05-13 13:26
What is a totipotent cell?
A cell that contains all the genetic information needed to make a whole new organism.
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Why must the nucleus from an adult cell be introduced to an egg cell for cloning?
The egg cytoplasm contains many important molecules needed to initiate and support early animal development.
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What changes in DNA accumulate with age?
Damage which can lead to cancers, fertility decreases abd the telomeres shorten with successive cell divisions.
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What major processes lead from a zygote to a complex organism?
Cell division (growth), pattern formation, morphogenesis, cell differentiation, cell death and cell migration.
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What are transcription factors?
Proteins that bind to DNA to regulate gene expression.
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What are homodimers?
Dimer of the same protein monomer.
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What are heterodimers?
Dimer between two different protein molecules.
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What is the direct mechanism for gene regulation?
The ligand-receptor complex directly enters the nucleus and binds to DNA to switch genes on or off.
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What are enhancers?
The short cis-regulatory sequences transcription factors bind to in order to activate transcription.
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Why can enhancers be distant from the promoter?
DNA looping brings the bound transcription factor coser to the promoter in 3D space allowing transcription to be initiated.
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Other cards in this set

Card 2

Front

Why must the nucleus from an adult cell be introduced to an egg cell for cloning?

Back

The egg cytoplasm contains many important molecules needed to initiate and support early animal development.

Card 3

Front

What changes in DNA accumulate with age?

Back

Preview of the front of card 3

Card 4

Front

What major processes lead from a zygote to a complex organism?

Back

Preview of the front of card 4

Card 5

Front

What are transcription factors?

Back

Preview of the front of card 5
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