Cancer

?
What is neoplastic transformation?
Conversion of a normal cell to a malignant cell
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BCR ABL kinases don't
Initiate denaturing of checkpoint proteins
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What does the tumour supressor gene do?
They code for proteins that control cell cycle progression/proliferation (many of which are check point genes.
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How is proliferation controlled in normal cells
Activate oncogenes transiently (i.e for a short by mitogens) and INactivate tumour suppressor genes transeintly
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How can Mitotic crossover play a role in cancer?
It is an event where a cancer causing reccesive allele may be expressed and thus predispose the cell causing development of cancer
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Other cards in this set

Card 2

Front

BCR ABL kinases don't

Back

Initiate denaturing of checkpoint proteins

Card 3

Front

What does the tumour supressor gene do?

Back

Preview of the front of card 3

Card 4

Front

How is proliferation controlled in normal cells

Back

Preview of the front of card 4

Card 5

Front

How can Mitotic crossover play a role in cancer?

Back

Preview of the front of card 5

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