Definitions

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1. Quantitative trait loci

  • Susceptibility genes increase a person’s likelihood of contracting a heritable illness
  • A loci that contributes to determining the phenotype of a continuous character
  • Characters that you either have or do not have (e.g. extra fingers)
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2. Oligogenic

  • When genetic determination involves a small number of loci
  • When a genetic determination involves many loci, each of small effect

3. What is the basal transcription apparatus

  • The complex that is required to initiate transcription by an RNA polymerase, it consists of the polymerase plus associated general transcription factors
  • The strand which is synthesised in steps, called Okazaki fragments, which are then ligated with DNA ligase
  • Short DNA sequences

4. Imprinting

  • Different members of the family show different features of the syndrome, due to other genes, environmental factors and chance
  • Certain human characters affect both sexes, but manifest only when inherited from a parent of a particular sex; this is because certain genes are imprinted with their parental origin
  • The tendency of some conditions to become more severe or have an earlier onset in successive generations

5. The non-template strand during RNA synthesis

  • Sense strand
  • Antisense strand

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