TOTIPOTENCY: Ability to produce all cell types including specialised and extraembryonic cells.
PLURIPOTENCY: Ability of a stem cell to produce specialised cell but not extraembryonic.
Undifferentiated become differentiated when they develop structure, due to differential gene expression.
STEM CELLS are UNDIFFERENTIATED: give rise to other cell types.
- EMBRYONIC STEM CELLS: found in embryos
Easy to extract and grow. Rejection and infections are possible.
- ADULT STEM CELLS: found in bone marrow
Rejection avoided, difficult to extract and infections possible. More difficult to produce cell types.
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