parentals

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  • Created by: anna888
  • Created on: 02-03-23 16:28
what does parentals refer to
anything other than gi, mainly injections
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describe iv route
into surface vein. over 1ml. isotonic soln. no water in oil, no suspensions, 100% bioavailability. infusions up to 3000ml with steady state drug release
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describe subcuteneous route
less than 1ml. in loose connective tissue layer, fast absorbtion as hghly vascularised, yes suspensions, yes aqueous solns
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describe intra artial route
local fast effect, emergencies only as invasive
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describe intradermal route
less than 0.3 ml. skin between epidermas and dermas, slow,
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describe intramuscualr route
less than 4ml. yes aqueous, yes oily, yes suspensions. slow
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describe intraspinal
all isotonic no preservatives. intrathecal= into csf into subarrachnoid fluid. 100% absorbtion, less than 10ml. epidural, between dura matter and vertebrae
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desribe intrarticular
into synovial fluid in joints, 100% local absorbtion, yes aqueous yes suspensions
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describe intra ocular
intracameral=infront of lens, 0.1-10ml. intravieral-into viterous chamber- less than 0.1ml
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advantages of parental route
rapid, high bioavailability, high conc, suitable for unconcious patient, infusion for steady state plasma level.
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disadvantages of parental route
requires health care profffesional, risks ie air embolism or needle injuries, needle fear, costs manufacturing and storage
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explain 2 pharmacopeail requirements
sterile- no endotoxins and pyrogens as bypasses defense mechanims. no particulates= blood vessles blocked
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describe glass ampoules
1-10ml. single use fradige type 1 glass
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describe plastic ampoules
more robust, more expensive and prone to drug absorbtion
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describe vials
type 1 glass, 5-100ml, alimuim cap to protect.
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describe infusion bags (3 types)
up to 3000ml. collapisble bags, semi rigid plastic bottles, glass bottles
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Other cards in this set

Card 2

Front

describe iv route

Back

into surface vein. over 1ml. isotonic soln. no water in oil, no suspensions, 100% bioavailability. infusions up to 3000ml with steady state drug release

Card 3

Front

describe subcuteneous route

Back

Preview of the front of card 3

Card 4

Front

describe intra artial route

Back

Preview of the front of card 4

Card 5

Front

describe intradermal route

Back

Preview of the front of card 5
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