IFN
- Created by: Martha Brown
- Created on: 16-05-15 01:54
View mindmap
- Viral infection
- TLR3 is stimulated
- TLR3 stimulates and activates IRF3
- IRF3 leads to the induction of IFN
- Leads to Type I response (IFN-alpha and IFN-beta)
- Causes ISGs (interferon stimulated genes) to be transcribed
- Interferes with viral replication and inhibits viral protein synthesis
- More important than IL-6
- Cell dies as ISGs stop viral proteins being produced so it turnoff self protein production too
- More important than IL-6
- Interferes with viral replication and inhibits viral protein synthesis
- Causes ISGs (interferon stimulated genes) to be transcribed
- Leads to Type I response (IFN-alpha and IFN-beta)
- IRF3 leads to the induction of IFN
- TLR3 stimulates and activates IRF3
- Produces IFN
- Increases the alertness of the immune system by increasing costimulatorymolecule expression
- Adaptive responses won't follow if the cell dies here
- TLR3 is stimulated
Comments
No comments have yet been made