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1. What is an adenoma?
- A benign neoplasm of cartilage
- A benign neoplasm of glandular epithelium
- A malignant neoplasm of glandular epithelium
- A malignant neoplasm of cartilage
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2. What is a proto-oncogene?
- A gene that is responsible for inducing apoptosis
- A normal gene that can undergo a mutation to become an oncogene
- A gene that protects a cell from one step on the path to cancer
- A gene which is inappropriately abnormally or excessively expressed in tumours and is responsible for their abnormal growth
3. Which of these is not true for malignant neoplasms?
- The neoplasm is well-differentiated.
- The growth rate of the neoplasm is relatively rapid.
- There are numerous mitotic figures within the neoplasm.
- The nuclei are hyperchromatic and pleopmorphic.
- The neoplasm does not have a true capsule and have an ill-defined border.
4. Which of these is a factor in the growth of transformed, tumour cells?
- Loss of contact inhibition and colony formation
- Early maturation
- Increased serum growth factor requirment
- Increased cohesion and being anchorage dependent
5. Which of these is the first step in proliferation of normal cells?
- The cell enters and progresses in the cell cycle
- A signal is transduced across the membrane
- A transduced signal is transmitted to the nucleus
- The cell divides in a controlled way
- A growth factor binds to and activated a cell surface growth factor receptor
- Nuclear regulatory factors that initiate DNA transcription are activated
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