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1. Which of these is not a feature used to determine the grade of a tumour?
- Secretion of proteolytic enzymes
- Mitotic activity
- Nuclear size
- Degree of differentiation
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2. What is a malignant neoplasm of striated muscle called?
- Liposarcoma
- Chondrosarcoma
- Osteosarcoma
- Rhabdomyosarcoma
- Leiomyosarcoma
3. Which of these disorders of cell growth is always pathological?
- Hypertrophy
- Metaplasia
- Dysplasia
- Hyperplasia
- Atrophy
4. Which of these is the first step in proliferation of normal cells?
- A growth factor binds to and activated a cell surface growth factor receptor
- Nuclear regulatory factors that initiate DNA transcription are activated
- The cell divides in a controlled way
- A transduced signal is transmitted to the nucleus
- A signal is transduced across the membrane
- The cell enters and progresses in the cell cycle
5. What does 'N' mean in the determination of the stage of a tumour?
- The depth of invasion.
- The degree of metastases.
- The number of lymph nodes involved.
- The nuclear size and pleomorphism.
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