Monoclonal antibodies

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What are antibodies produced by?
B-lymphocytes
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How are monoclonal antibodies produced?
From lots of clones of one single white blood cell
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What does it mean if the antibodies are monoclonal?
They are all identical and only target a specific protein antigen
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How can a Hybridoma cell be created?
By fusing a mouse B- lymphocyte with a tumour cell
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Why are monoclonal antibodies really useful?
They can bind to target a specific cell or chemical in the body because of the antigen on it's surface
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What happens to the hybridoma cell once created?
Can be cloned to produce many identical antibodies
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What can monoclonal antibodies be used to diagnosis?
Weather a woman is pregnant/not
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What are tumour markers?
Cancer cells have different antigens attached to their cell membranes called this
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What is attached to the monoclonal antibodies to treat cancer?
A anti-cancer drug or radioactive substance can be attached to stop the cancer cells growing or dividing
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What is the advantage of using monoclonal antibodies to treat cancer?
They only target cancer cells not normal cells
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What is the disadvantage of using monoclonal antibodies?
They have more side effects than expected
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What can monoclonal antibodies be used to?
Locate a specific molecule on cell/tissue by attaching it to a fluorescent dye to detect them
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Other cards in this set

Card 2

Front

How are monoclonal antibodies produced?

Back

From lots of clones of one single white blood cell

Card 3

Front

What does it mean if the antibodies are monoclonal?

Back

Preview of the front of card 3

Card 4

Front

How can a Hybridoma cell be created?

Back

Preview of the front of card 4

Card 5

Front

Why are monoclonal antibodies really useful?

Back

Preview of the front of card 5
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