Higher human biology Unit 1.4

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1. What are 3 types of substitution mutation?

  • Missense, non-site and splice-site
  • Missense, nonsense and splice-site
  • Missing, nonsense and splice-site
  • Missense, nonsense and splicing
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2. What happens in a deletion chromosome mutation?

  • A section of genes is deleted from the chromosome resulting in a shorter chromosome
  • A section of genes from a non-homologous chromosome is added or inserted into the chromosome
  • A section of nucleotides are deleted from a gene.
  • a section of the chromosome is reversed.

3. What effect does a missense mutation have on the protein being made?

  • The protein will be unchanged
  • One nucleotide is changed so the protein may still be functional depending on the role of that amino acid in the final protein
  • One amino acid is changed so the protein may still be functional depending on the role of that amino acid in the final protein
  • One amino acid is changed so the protein will be shorter and not function

4. What are 4 types of chromosome mutation?

  • Deletion, duplication, inversion and translocation
  • substitution, duplication, inversion and translocation
  • Deletion, duplication, substitution and translocation
  • Deletion, duplication, inversion and transcription

5. What type of nucleotide changes cause a frameshift mutation?

  • insertion only
  • deletion only
  • Insertion and deletion
  • substitution

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