Diabetes

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How do biguanides (metformin) work?
Activate AMP kinase and decreases hepatic glucose production, intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake
1 of 6
which anti-diabetic agent is used in pregnancy?
insulin
2 of 6
Which anti-diabetic agent is most likely to cause weight loss?
Metformin
3 of 6
What is the first line treatment in T2DM with HF or CVD?
SGLT2 inhibitors
4 of 6
What is the MOA of sulphonylureas?
Inactivates ATP sensitive K+ channel which increases Ca2+ influx and thus insulin secretion. Also increases glucose sensitivity in beta cells and lowers hepatic glucose production.
5 of 6
What is the first recommended basal insulin therapy of a basal-bolus insulin regimen?
Detemir
6 of 6

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Card 2

Front

which anti-diabetic agent is used in pregnancy?

Back

insulin

Card 3

Front

Which anti-diabetic agent is most likely to cause weight loss?

Back

Preview of the front of card 3

Card 4

Front

What is the first line treatment in T2DM with HF or CVD?

Back

Preview of the front of card 4

Card 5

Front

What is the MOA of sulphonylureas?

Back

Preview of the front of card 5
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