S2W5 ACE inhibitors and angiotensin II receptor antagonists 0.0 / 5 ? OtherPharmacodynamicsUniversityNone Created by: Tino MurondaCreated on: 08-03-21 10:36 What are some examples of ACE inhibitors end in -pril Catopril, Ramipril, Enalpril 1 of 12 What is the mechanism of action of ACE inhibitors? Block ACE - responsible for converting angiotensin I to angiotensin II. This reduces angiotensin II levels 2 of 12 What are some clinical uses of ACE inhibitors? Heart failure, Diabetic nephropathy, Hypertension, Diabetic retinopathy, post myocardial infarction 3 of 12 What are some contraindicatons of ACE inhibtors? Renal artery stenosis, pregnancy, low BP 4 of 12 What are some side effects of ACE inhibitors? Hypotension, angiodema,dry cough,neuropathy,skin rash, hyperkalaemia, loss of taste 5 of 12 What are some examples of angiotensin II receptor blockers? end in -artan Losartan, Telmisartan, Candesartan, Valsartan 6 of 12 What is the mechanismof action of angiotensin II blockers? Block angiotensin II type I receptors causing vasodilation due to lower levels of angiotensin II. 7 of 12 What are some clinical uses of angiotensin II receptor blockers? Hypertension, Heart failure, Albuminuria, Left ventricular hypertrophy 8 of 12 What are some side effects of Angiotensin II receptor blockers? Mild side effects: dizziness, hypotension, fatigue, hyperkalaemia, Acute kidney injury 9 of 12 What are some contraindications of angiotensin II receptor blockers? Renal artery stenosis, pregnancy and breast feeding, peripheral vascular disease, low BP, Taking NSAIDs 10 of 12 What did the ELITE study find when patients took angiotensin II receptor blocker losartan? Mortality was 46% lower 11 of 12 What did the AIRE study find about the ACE inhibitor ramipril? Mortality was reduced by 27% 12 of 12
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