Describe & Evaluate explanations for disorders of memory (studies)

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  • Created by: fransmith
  • Created on: 05-06-16 15:32
Clive Wearing (A)
Had encephalitis, caused damage to the hippocampus, cannot transfer info from STM to LTM, anterograde&retrograde, procedural memory intact
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Isaac & Mayes (A)
Amnesiacs performed as well as controls on cued recall and recognition - problems with consolidation not retrieval
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Gabrieli (A)
Damage to just part of the hippocampus = anterograde amnesia alone
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Reed & Squire (A)
MRI - 4 patients with retro - all had hippocampus damage, worst had lesions in temporal lobe too - role of hippocampus & other structures
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Remondes & Schman (A)
Rats with damaged hippocampus - learn a maze but forgot quickly - make new memories but not consolidate - hippocampus associated with consolidation - cannot be app to humans
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Yarnell & Lynch (A)
American footballers had been concussed - what strategy team was using? - could remember straight after but forgot after 20 mins - concussion prevented consolidation into LTM
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Benton (A)
Confusion & retrograde less for unilateral ECT
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Friedberg (A)
After ECT takes 5-10 mins for patients to remember who they are, where they are & what day it is
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Zubin (A)
Memory loss from ECT can be extensive - forget children & how to cook
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HM (Milner) (A)
Following operation on lobes (most if hippocampus - important for declarative memory -removed) to treat epilepsy - suffered retrograde - couldn't remember staff he'd known for years - procedural :), declarative :(
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Corkin (A)
HM could learn new skills but had to be reminded of this - procedural was intact but declarative was impaired
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Berant et al (A)
Anaesthesia accompanying surgery can cause amnesia in elderly patients - retrograde in 60-80 y/o after surgery - surgery can have an effect on memory
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Cermak et al (A)
Korsakoff patients still has procedural memories intact
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Bentson et al (AD)
B-amyloid also interferes with a neurotransmitter involved in learning
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Murphy & LeVine (AD)
B-amyloid triggers chain of events that continues irrespective of B-amyloid levels, yet to be tested & consequences not identified - formation of tangles may be an important effect
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Cummings (AD)
Dogs have more B-amyloid with age, correlating with cognitive dysfunction
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Lott (AD)
Most people with down's syndrome who reach middle age get early onset of AD
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Hendrie (AD)
Cross-cultural - Nigeria & USA - Frequency of genes related to AD similar but Nigerians suffered less - environmental factors e.g. diet?
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Study for Health Survey England 2000 (AD)
Correlation between low levels of vitamin D and dementia - supports idea that diet could play a part
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Other cards in this set

Card 2

Front

Amnesiacs performed as well as controls on cued recall and recognition - problems with consolidation not retrieval

Back

Isaac & Mayes (A)

Card 3

Front

Damage to just part of the hippocampus = anterograde amnesia alone

Back

Preview of the back of card 3

Card 4

Front

MRI - 4 patients with retro - all had hippocampus damage, worst had lesions in temporal lobe too - role of hippocampus & other structures

Back

Preview of the back of card 4

Card 5

Front

Rats with damaged hippocampus - learn a maze but forgot quickly - make new memories but not consolidate - hippocampus associated with consolidation - cannot be app to humans

Back

Preview of the back of card 5
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