Had encephalitis, caused damage to the hippocampus, cannot transfer info from STM to LTM, anterograde&retrograde, procedural memory intact
1 of 19
Isaac & Mayes (A)
Amnesiacs performed as well as controls on cued recall and recognition - problems with consolidation not retrieval
2 of 19
Gabrieli (A)
Damage to just part of the hippocampus = anterograde amnesia alone
3 of 19
Reed & Squire (A)
MRI - 4 patients with retro - all had hippocampus damage, worst had lesions in temporal lobe too - role of hippocampus & other structures
4 of 19
Remondes & Schman (A)
Rats with damaged hippocampus - learn a maze but forgot quickly - make new memories but not consolidate - hippocampus associated with consolidation - cannot be app to humans
5 of 19
Yarnell & Lynch (A)
American footballers had been concussed - what strategy team was using? - could remember straight after but forgot after 20 mins - concussion prevented consolidation into LTM
6 of 19
Benton (A)
Confusion & retrograde less for unilateral ECT
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Friedberg (A)
After ECT takes 5-10 mins for patients to remember who they are, where they are & what day it is
8 of 19
Zubin (A)
Memory loss from ECT can be extensive - forget children & how to cook
9 of 19
HM (Milner) (A)
Following operation on lobes (most if hippocampus - important for declarative memory -removed) to treat epilepsy - suffered retrograde - couldn't remember staff he'd known for years - procedural :), declarative :(
10 of 19
Corkin (A)
HM could learn new skills but had to be reminded of this - procedural was intact but declarative was impaired
11 of 19
Berant et al (A)
Anaesthesia accompanying surgery can cause amnesia in elderly patients - retrograde in 60-80 y/o after surgery - surgery can have an effect on memory
12 of 19
Cermak et al (A)
Korsakoff patients still has procedural memories intact
13 of 19
Bentson et al (AD)
B-amyloid also interferes with a neurotransmitter involved in learning
14 of 19
Murphy & LeVine (AD)
B-amyloid triggers chain of events that continues irrespective of B-amyloid levels, yet to be tested & consequences not identified - formation of tangles may be an important effect
15 of 19
Cummings (AD)
Dogs have more B-amyloid with age, correlating with cognitive dysfunction
16 of 19
Lott (AD)
Most people with down's syndrome who reach middle age get early onset of AD
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Hendrie (AD)
Cross-cultural - Nigeria & USA - Frequency of genes related to AD similar but Nigerians suffered less - environmental factors e.g. diet?
18 of 19
Study for Health Survey England 2000 (AD)
Correlation between low levels of vitamin D and dementia - supports idea that diet could play a part
19 of 19
Other cards in this set
Card 2
Front
Amnesiacs performed as well as controls on cued recall and recognition - problems with consolidation not retrieval
Back
Isaac & Mayes (A)
Card 3
Front
Damage to just part of the hippocampus = anterograde amnesia alone
Back
Card 4
Front
MRI - 4 patients with retro - all had hippocampus damage, worst had lesions in temporal lobe too - role of hippocampus & other structures
Back
Card 5
Front
Rats with damaged hippocampus - learn a maze but forgot quickly - make new memories but not consolidate - hippocampus associated with consolidation - cannot be app to humans
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