Carrying oxygen and carbon dioxde 0.0 / 5 ? BiologyVeterinary medicineUniversityNone Created by: ezCreated on: 26-12-13 20:19 How many subunits does myoglobin contain? One 1 of 26 What is a prosthetic group? A group inserted into a protein post-translation 2 of 26 What is the prosthetic group of Haemoglobin? The haem group 3 of 26 What does the proximal histidine do? Binds to the iron ion, distorting the haem group 4 of 26 Which is a non-allosteric enzyme? Myoglobin 5 of 26 Which demonstrates sigmoid dependency on the substrate concentration? Haemoglobin 6 of 26 What is BPG an example of? Negative allosteric inhibitor of Hb 7 of 26 What effect does increasing pO2 have on Hb? It shifts the equilibrium so more Hb exists in the oxy state 8 of 26 When is myoglobin's affinity for O2 at its lowest? In very low O2 levels 9 of 26 What is the primary function of myoglobin? A store of oxygen that only releases O2 in very low pO2 conditions 10 of 26 What does CO2 binding to Hb do? Stabilises the deoxy state 11 of 26 What does a lower pH do? Stabilises the deoxy Hb state, increasing O2 unloading 12 of 26 What is BPG produced from? Glycolysis 13 of 26 Where is BPG commonly found? Erythrocytes 14 of 26 Why does foetal Hb have a higher O2 affinity at lower pO2? BPG binds less tightly to foetal Hb 15 of 26 What is the structure of adult Hb? 2alpha, 2beta 16 of 26 What causes sickle cell anaemia? A single amino acid change in the beta chain 17 of 26 What is a characteristic of HbS? Formation of long insoluble filaments in deoxy form 18 of 26 How is the majority of oyxgen carried? Bound to haemoglobin 19 of 26 Where is the affinity of Hb for O2 highest? In the systemic arteries 20 of 26 What effect does increasing temperature have on Hb? It reduces the affinity for O2 21 of 26 Which has a larger Hb saturation at a give pO2? Larger mammals 22 of 26 Which Hb is unaffected by 2,3BPG? Ruminant 23 of 26 Apart from dissolved in plasma and bound to proteins like Hb, how is CO2 carried in the blood? As HCO3- ions, CO3- ions and H2CO3 24 of 26 How is the majority of CO2 transported? Dissolved in plasma 25 of 26 Which is more soluble in water? CO2 26 of 26
Comments
No comments have yet been made