Cancer

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1. What is neoplastic transformation?

  • a gene when mutated or expressed at a high level turns a normal cell into a malignant one
  • cooperation of multiple genetic changes within a cell
  • Causes a permanent activation
  • Conversion of a normal cell to a malignant cell
  • A gene which encodes signalling molecules that can act as Growth factors, protein kinases and transcription factors that activates gene expression
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Other questions in this quiz

2. Which of these is incorrect about Philiadelphia chromosome?

  • occurs between chromosomes 9 and 21 by reciprocal translocation
  • BCR - ABL fusion gene encodes BCR ABL kinases -which is unique to Lukemia cells

3. How can Mitotic crossover play a role in cancer?

  • It is an event where a cancer causing dominant allele is sometimes expressed and thus predispose the cell causing development of cancer
  • It is an event where a cancer causing reccesive allele may be expressed and thus predispose the cell causing development of cancer
  • It does not play a role

4. Which of these is correct for a normal cell?

  • By reducing the immune barrier
  • Continue cell proliferation
  • balance between the growth promoting and restriction factors
  • Apoptosis doesn't occur
  • Loss of differentiation
  • balance process disrupted

5. BCR ABL kinases don't

  • initiate abnormal signalling pathways
  • Initiate denaturing of checkpoint proteins
  • initiate deregulation of signalling network
  • transcriptional deregulation of cell

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