Other questions in this quiz

2. Which of these is incorrect about Philiadelphia chromosome?

  • occurs between chromosomes 9 and 21 by reciprocal translocation
  • BCR - ABL fusion gene encodes BCR ABL kinases -which is unique to Lukemia cells

3. Which of these is correct for a normal cell?

  • balance process disrupted
  • Loss of differentiation
  • By reducing the immune barrier
  • Apoptosis doesn't occur
  • balance between the growth promoting and restriction factors
  • Continue cell proliferation

4. How is proliferation controlled in normal cells

  • Activate oncogenes transiently (i.e for a short by mitogens) and INactivate tumour suppressor genes transeintly
  • Uncontroled activation of oncogenes and deactivation of tumour supressor genes

5. What is neoplastic transformation?

  • Causes a permanent activation
  • cooperation of multiple genetic changes within a cell
  • Conversion of a normal cell to a malignant cell
  • a gene when mutated or expressed at a high level turns a normal cell into a malignant one
  • A gene which encodes signalling molecules that can act as Growth factors, protein kinases and transcription factors that activates gene expression

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