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6. Which of these is correct for a normal cell?

  • Loss of differentiation
  • Apoptosis doesn't occur
  • By reducing the immune barrier
  • balance process disrupted
  • balance between the growth promoting and restriction factors
  • Continue cell proliferation

7. What does the tumour supressor gene do?

  • They code for proteins that control cell cycle progression/proliferation (many of which are check point genes.
  • They code for signalling proteins that codes signalling molecules e.g growth factors, protein kinase and transcription factor
  • e.g.P35 gene encoded by the TP53 gene on the short arm of chromosome 17 and regulates cell cycle
  • Can't induce growth arrest at G1/S regulation point (restriction point)
  • The proteins can't initiate apoptosis if DNA damage is irreparable