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6. Which of these is correct for a normal cell?
- Loss of differentiation
- Apoptosis doesn't occur
- By reducing the immune barrier
- balance process disrupted
- balance between the growth promoting and restriction factors
- Continue cell proliferation
7. What does the tumour supressor gene do?
- They code for proteins that control cell cycle progression/proliferation (many of which are check point genes.
- They code for signalling proteins that codes signalling molecules e.g growth factors, protein kinase and transcription factor
- e.g.P35 gene encoded by the TP53 gene on the short arm of chromosome 17 and regulates cell cycle
- Can't induce growth arrest at G1/S regulation point (restriction point)
- The proteins can't initiate apoptosis if DNA damage is irreparable