Platelets are cytoplasmic fragments of larger cells called _________
Megakaryocytes
1 of 20
____________ are essential for the clotting process that occurs when blood vessels are ruptured
Platelets
2 of 20
Platelets age quickly and last around _____ days if they aren't involved in clotting
10
3 of 20
Platlets are kept mobile but inactive by ________ and prostacyclin, which are secreted by endothelial cells lining the blood vessels
Nitric oxide
4 of 20
What hormone regulates the formation of platelets?
Thrombopoietin
5 of 20
The megakaryoblast repeatedly mitoses but _________ does not occure, resulting in a stage IV megakaryocyte
Cytokinesis
6 of 20
The mature megakaryoblast presses against a sinusoid in the _________ and sends cytoplasmic extensions through the _______ wall, which rupture and release platelets into the bloodstream
Red marrow, sinusoid
7 of 20
The series of reactions set in motion to stop bleeding after a blood vessel wall breaks
Haemostasis
8 of 20
There are essentially three steps to haemostasis: vascular spasm, platelet plug formation and ___________
Coagulation
9 of 20
During vascular spasm, blood vessels ____________ to significantly reduce blood loss
Constrict
10 of 20
Vascular spasm can reduce blood loss for about ________ minutes
20 - 30
11 of 20
When platelets aggregate and stick together, which step in haemostasis is this?
Platelet plug formation
12 of 20
Which plasma protein stabilises bound platelets and collagen fibers?
Von Willebrand factor
13 of 20
When platelets adhere to collagen, they release chemical messengers including: _______, serotonin and thromboxane A2
Adenosine diphosphate
14 of 20
Name the potent aggregating agent released by platelets that causes more platelets to stick and release their contents
Adenosine diphosphate
15 of 20
____________ and thromboxane A2 enhance vascular spasm and platelet aggregation
Serotonin
16 of 20
Platelet plug formation is a ___________ feedback cycle, that takes around a minute to form
Positive
17 of 20
Coagulation reinforces platelet plug with __________ that act as glue
Fibrin threats
18 of 20
In most cases activation turns most clotting factors into _________
Enzymes
19 of 20
There are ___ phases to coagulation
3
20 of 20
Other cards in this set
Card 2
Front
____________ are essential for the clotting process that occurs when blood vessels are ruptured
Back
Platelets
Card 3
Front
Platelets age quickly and last around _____ days if they aren't involved in clotting
Back
Card 4
Front
Platlets are kept mobile but inactive by ________ and prostacyclin, which are secreted by endothelial cells lining the blood vessels
Back
Card 5
Front
What hormone regulates the formation of platelets?
Comments
No comments have yet been made