Susceptibility

According to the World Health Organisation (WHO) most diseases involve environmental factors and the complex interaction of many genes.
Although an individual may not be born with a disease, their genetics may make them susceptible to acquiring it later in life.
The diseases that are moe likely to happen in individuals with susceptibility include, cancer, diabetes and high blood cholesterol.

Susceptibility = an increased likelihood of acquiring a disease because of an individuals genetic make up.

Over 200 types
Cell disease that results in cells becoming abnormal and dividing to create more abnormal cells.
Most attributed to environmental and lifestyle factors.
Lung cancer is linked to tobacco use and skin cancer is linked to over exposure to the sun light (ultraviolet light)
It is estimated that over 40% of cancers can be prevented by making different lifestyle choices and avoiding certain environmental factors.
Some people are at more risk because they have inherited faults.
Cancers with a genetic link include: breasts, bowel, womb and kidney.
Faulty gene doesn't mean that someone will get cancer but lifestyle choices may increase the risk.

Lifestyle factors:
Smoking
Alcohol
Diet
Exercise

Environmental factors:
Sun exposure
Asbestos (dust)

Chronic condition
Approximately 1 in 16 people in the U.K. have diabetes.
Type 1 (early onset/insulin dependant) strong predisposition. There is a greater risk if one or both biological parents have diabetes.
Type 2 (later/mature onset) environment and lifestyle play a greater role.

Cholesterol is a fatty substance that is carried around the body by protein .
Too much cholesterol can build up in the artery walls and lead to heart disease and other cardiovascular diseases.
Lifestyle : smoking, diet and lack of exercise.
Caused by an inherited condition - hypercholesterolemia
Caused by a gene alteration inherited from a parent
Perople are born with this and it can lead to early heart problems if left untreated.