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Muscle action
8.2 Neuromuscular junctions, types of muscle and the sliding filaments model

Muscles and joints
Muscles can work in antagonistic pairs. In order for smooth movement at a muscular junction, such as the elbow, two
muscles must be involved. A muscle can only produce a force when it…

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A nerve impulse which arrives at the neuromuscular junction is transmitted across the gap via a method very similar to
that of the cholinergic synapse (see 1.4 Synapses for details on the nerve junction, because you are expected to be able to
compare similarities and differences between the two) and…

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Cells of skeletal muscle are The cells of smooth muscle appear spindle- Cardiac muscle cells also appear
large cells, long and thin, and shaped, with small gaps (fenestrations) in striated (banded) but are not to
are multinucleated cells (have between them, and the cells are singly- be confused with skeletal…

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So there are two components of the sliding filament model. The thin filament consists of two thin strands of actin, a
globular protein, coiled around each other. Surrounding them is another rod-shaped protein called tropomyosin which
coils around the actin. The role of tropomyosin is to reinforce the actin strands.…


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