CHD
- Created by: Emilefree
- Created on: 02-04-15 12:58
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- CHD
- Atheroma
- Fatty Streaks
- Accumulation of white blood cells that have taken up LDLs
- Enlarge to form an atheromatous plaque
- Reduces size of lumen
- Thrombosis
- If atheroma breaks through endothelium of blood vessel a rough surface is created.
- Forms a blood clot or thrombus
- Blocks the blood vessel meaning region of tissue is blocked off and dies
- Forms a blood clot or thrombus
- If atheroma breaks through endothelium of blood vessel a rough surface is created.
- Thrombosis
- Reduces size of lumen
- Aneurysm
- Myocardial Infarction
- Refers to a reduced supply of oxygen to the muscles of the heart
- Results from a blockage in a coronary artery
- Thrombosis
- If atheroma breaks through endothelium of blood vessel a rough surface is created.
- Forms a blood clot or thrombus
- Blocks the blood vessel meaning region of tissue is blocked off and dies
- Forms a blood clot or thrombus
- If atheroma breaks through endothelium of blood vessel a rough surface is created.
- Myocardial Infarction
- Fatty Streaks
- Risk factors
- Smoking
- Carbon monoxide
- Binds irrevesibly to haemoglobin
- Reduces oxygen-carrying capacity of blood
- Heart must work harder, raising blood pressure
- Insufficient amount of oxygen to supply heart with during exercise
- Leads to angina or myocardial infarction
- Reduces oxygen-carrying capacity of blood
- Binds irrevesibly to haemoglobin
- Nicotine
- Stimulates production of adrenaline
- Which raises blood pressure
- Makes platelets sticky so a higher risk of thrombosis
- Stimulates production of adrenaline
- Carbon monoxide
- Blood cholesterol
- Essential component of membranes
- Carried in plasma as tiny spheres of lipoproteins
- HDLs
- Remove cholesterol from tissues and transports to liver for excretion
- Protects against CHD
- Remove cholesterol from tissues and transports to liver for excretion
- LDLs
- Transports cholesterol from liver to tissues
- Leads to development of atheroma and CHD
- Transports cholesterol from liver to tissues
- Essential component of membranes
- Diet
- High levels of salt=increase in BP
- High levels of unsaturated fat
- Increase in LDL levels
- Smoking
- Atheroma
- Atheroma weakens artery wall, which swells up
- Bursts leading to haemorrhage and loss of blood to region
- Aneurysm
- Myocardial Infarction
- Refers to a reduced supply of oxygen to the muscles of the heart
- Results from a blockage in a coronary artery
- Myocardial Infarction
- High blood pressure
- Already high pressure in arteries so heart must work harder to pump blood into them
- More prone to failure
- High BP in arteires increases likelihood of developing aneurysm, causing haemorrhage
- To resist high BP, artery walls thicken & harden narrowing lumen and restricting bloodflow
- Risk factors
- Smoking
- Carbon monoxide
- Binds irrevesibly to haemoglobin
- Reduces oxygen-carrying capacity of blood
- Heart must work harder, raising blood pressure
- Insufficient amount of oxygen to supply heart with during exercise
- Leads to angina or myocardial infarction
- Reduces oxygen-carrying capacity of blood
- Binds irrevesibly to haemoglobin
- Nicotine
- Stimulates production of adrenaline
- Which raises blood pressure
- Makes platelets sticky so a higher risk of thrombosis
- Stimulates production of adrenaline
- Carbon monoxide
- Blood cholesterol
- Essential component of membranes
- Carried in plasma as tiny spheres of lipoproteins
- HDLs
- Remove cholesterol from tissues and transports to liver for excretion
- Protects against CHD
- Remove cholesterol from tissues and transports to liver for excretion
- LDLs
- Transports cholesterol from liver to tissues
- Leads to development of atheroma and CHD
- Transports cholesterol from liver to tissues
- Essential component of membranes
- Diet
- High levels of salt=increase in BP
- High levels of unsaturated fat
- Increase in LDL levels
- Smoking
- Already high pressure in arteries so heart must work harder to pump blood into them
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