What's In A Medicine? Quiz
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- Created by: ChloeD1995
- Created on: 17-10-12 12:12
The Bronsted-Lowry Theory defines Acids and Alkalis in terms of...
Protons
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In Mass Spectrometry, molecules are...
bombarded with high-speed electrons
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The base peak on a mass spectrum graph is the...
Highest, most common peak
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Bronsted-Lowry bases have a...
Lone pair of electrons
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Carbonyl groups are present in...
Aldehydes and Ketones
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Aldehydes end in...
al
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Ketones are produced by oxidising...
secondary alcohols
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When ethanol is refluxed it produces
ethanoic acid
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When acidified potassium dichromate solution is added to a ketone, what colour would the ORANGE solution go?
Orange
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When acidified Potassium dichromate sol. is added to a ketone, what does the colour change mean?
Ketone is not reduced
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When an aldehyde reacts with HCN, what is the product called?
Hydroxynitriles
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The first step of nucleophilic addition is...
fast
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An example of instrumental analysis is...
Mass Spectrometry
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Carboxylic acids contain the .... group.
Carboxyl
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An OH- group on a benzene ring is a
phenol
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An acid is a
proton donor
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Iron (III) chloride is the test for a -
phenol
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Carboxylic acids and phenols react with bases to form
salts
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Only - can evolve Carbon Dioxide from a carbonate.
Carboxylic acid
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What colour does FeCl3 go in the presence of a phenol?
Purple
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What colour does FeCl3 go in the presence of an alcohol?
Orange
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When a carboxylic acid and an alcohol react together they form a...
Ester
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When you react a carboxylic acid and alcohol to produce an ester, what conditions are required?
reflux and conc. sulphuric acid
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Test for the phenol in 2-hydroxybenzoic acid is...
FeCl3
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Test for the carboxylic acid in 2-hydroxybenzoic acid is...
Na2CO3 producing effevescence, warming with methanol/H+ producing fruity smell
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Infrared spectroscopy uses
IR radiation of specific frequencies
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In a Infrared spectroscopy graph, the wavenumbers below 1500 are...
the fingerprint region
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In Mass Spectrometry, the molecule that is a positive ion is:
a molecular ion (M+)
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When the molecular ion fragments, there are...
another positively charged ion and a radical
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When you label a peak on the spectrum, you must write on the...
Charge (+)
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High resolution Mass Spectrometry can
define relative masses very accurately
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Medicinal chemicals should be synthesised because....
They are difficult to obtain from natural sources in great quantities
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All esters have the - group in them.
COO
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Esters smell of
fruit
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The reaction between carboxylic acids and alcohols produce...
An ester and water
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Alcohols and carboxylic acids require ---- to react.
Reflux, conc. sulphuric acid catalyst
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Phenols will not react with carboxylic acids, they must react with....
acyl chloride or acid anhydride
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Thin Layer Chromatography is a - test.
Qualitative
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The reaction with the highest atom economy is...
Rearrangement/Addition
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Combinatorial Chemistry is used to
Synthesise a large amount of similar compunds
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When an acid donates a proton this is a.... reaction
acid-base reaction
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H3O+ is...
an oxonium ion
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Conjugate bases come from...
Alkalis
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When a substance can act as an acid and alkali, it is:
Amphoteric
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A 'lead compund' is
the compound which shows promise
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In drug development, Development research is
Animal testing
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The main aim of Phase III Clinical trials is to identify...
Is it better than the standard treatment?
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Why does it take so long to develop new drugs?
Fear of litigation and search for 'silver bullet' medicines
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Other cards in this set
Card 2
Front
In Mass Spectrometry, molecules are...
Back
bombarded with high-speed electrons
Card 3
Front
The base peak on a mass spectrum graph is the...
Back
Card 4
Front
Bronsted-Lowry bases have a...
Back
Card 5
Front
Carbonyl groups are present in...
Back
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