The Neuromuscular Junction - Medicine BM5 NLM1

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1. What is denervation hypersensitivity?

  • No voluntary or involuntary muscle contraction, no resting muscle tone and no active resistance to stretch
  • Muscle wasting, loss of contractile protein
  • Redistribution of ACh receptors away from motor end plates causing reactivity to ACh along the length of the muscle fibre
  • Spontaneous twitching of motor units due to denervation hypersensitivity
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Other questions in this quiz

2. Through what mechanism is ACh released from the presynaptic membrane?

  • Sodium-dependent endocytosis
  • Calcium-dependent endocytosis
  • Calcium-dependent exocytosis
  • Sodium-dependent exocytosis

3. Select the structure which can be found most posterior in the spinal cord.

  • Dorsal horn
  • Central canal
  • Ventral horn
  • Lateral horn

4. What range of muscle fibres can one LMN innervate?

  • 1-100 muscle fibres
  • 10-1000 muscle fibres
  • 1000-10000 muscle fibres
  • 10-10000 muscle fibres

5. True or false: Very high frequencies of stimuli will result in tetanus (smooth contraction resulting in generation of maximum tension)?

  • Pass
  • True
  • False
  • 1914


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