Acute weakness 2 0.0 / 5 ? MedicineNeurologyUniversityAll boards Created by: zCreated on: 14-03-16 17:16 Spinal cord organisation 1 of 6 Spinal cord organisation 2 2 of 6 Peripheral nervous system pathology Anterior horn cell MND, polio Spinal root radiculopathy plexus brachial neuritis peripheral nerve neuropathy neuromuscular junction MG, LEMS muscle myopathy, dystrophy 3 of 6 Motor control lesions along primary motor pathway: weakness, paralysis UMN no wasting incr tone, clonus pyramidal weakness incr reflexes extensor (upgoing plantars) LMN wasting, fasciculation flaccid/decr tone weakness decr reflexes flexor/downgoing/normal plantars NMJ no wasting, normal tone, normal reflexes, flexor plantars weakness (fatiguability) 4 of 6 Motor control 2 lesion in: muscle wasting, no fasciculation normal (decr) tone normal (decr) reflexes flexor plantars cerebellum no weakness incoordination cranials: nystagmus, dysarthria/ limbs: FN, HS and gait ataxia intention tremor dysdiadochokinesis basal ganglia now eakness hypokinetic movement (Parkinson's) or hyperkinetcic movement (Huntingdon's) sensation - now eakness, sensory ataxia (partial compensation by vision) 5 of 6 Sensory loss sacral loss + urinary retention = cauda equina syndrome acute severe back pain sensory and motor "cape" loss (C4-T2) = syringomyelia chronic progressive disease in which longitudinal cavities form in the cervical region of the spinal cord pain, temp loss + controlateral motor, vibration loss = Brown-sequard syndrome lesion in one lateral half of the spinal cord 6 of 6
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