The Genome 0.0 / 5 ? PharmacyCellular PhysiologyUniversityNone Created by: SamDaviesCreated on: 02-05-18 20:56 24107913856 Across 1. Many bundles of nucleosomes. Many of these form loops which are then condensed and form chromosomes (9) 5. An RNA that has the same codon as an mRNA sequence which "picks up" amino acids with the complementary codon and delivers them to ribosomes to be added to a peptide chain (4) 6. Regions of DNA that are discarded after gene transcription, so RNA is not an identical copy of DNA. (Exons are those still expressed) (7) 7. This is formed at the end of gene transcription. Poly-adenylate polymerase adds many adenines to the end of the pre-RNA to terminate transcription (4, 1, 4) Down 2. Highly condensed region of interphase chromosome. Most abundant in cells which are less active (15) 3. A multiprotein complex consisting of TATA binding proteins (TBP) and TBP associating factors (TAF). It recognises the DNA sequence of the TATA box and binds to it, causing a 'kink' in the DNA (5) 4. The enzyme which adds free nucleotides to the strand (3, 10) 8. The DNA strand which (during DNA replication) undergoes replication discontinuously in small fragments (7) 9. This enzyme breaks the hydrogen bonds between bases of DNA (3, 8) 10. A short sequence of DNA found ~25bp upstream (near 5' end) from the start of transcription (4, 3)
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