Cell division cycle 0.0 / 5 ? PharmacyPH1122UniversityNone Created by: EmmanuelakyeCreated on: 21-01-20 15:11 what is cell cyle x1 mother cell produces x2 daughter cells 1 of 26 G1 is cell growth 2 of 26 S phase is dna in genome replicated 3 of 26 g2 is check for replication errors 4 of 26 m phase is chromosomes partitioned into x2 daughter cells 5 of 26 what is restriction point point late in g1 when growth factors are available 6 of 26 what is quiescent stage (g0) when growth factors unavailable 7 of 26 replicative senescence state where cells permenantly enter g0 due to not replicating anymore 8 of 26 prophase chromosomes condense, mitotic spindle forms 9 of 26 prometaphase Nuclear membrane disintegrates, Spindles attach to kinetochores 10 of 26 metaphase chromosomes align at equator 11 of 26 anaphase Sister chromatids separate, Pulled towards spindle poles 12 of 26 telophase Chromosomes arrive at poles, Nuclear envelopes reform 13 of 26 cytokinesis Cytoplasm divides resulting in two genetically near-identical cells 14 of 26 what are cdk's activated by cyclins 15 of 26 what are cdk's enzymes (kinase) phosphorylate protein to activate/deactivate them 16 of 26 What is the response to damaged or unreplicated dna arrest cells in g2 17 of 26 what is the response to damaged dna arrest cell cycle in g1 18 of 26 what is the response to daughter chromosomes not properly aligned on the mitotic spindle arrest mitosis in m phase 19 of 26 what is p53 transcription factor that incr when dna damaged 20 of 26 what does p53 do growth arrest, DNA repair and apoptosis (cell death) 21 of 26 cdk inhibits cell cycle 22 of 26 pcna inhibits dna replication 23 of 26 features of necrosis cell swelling,lysis 24 of 26 features of apoptosis Cell rounds and shrinks, DNA systematically fragmented. 25 of 26 how do chemotherapeutic agents stop cell division block dna replication and mitosis 26 of 26
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