Cancer genes and tumourigenesis 0.0 / 5 ? PharmacyPH1122UniversityNone Created by: EmmanuelakyeCreated on: 03-02-20 14:45 what is tumorigenesis a form of somatic evolution 1 of 16 how is tumour development characterised by multiple rounds of mutation and selection 2 of 16 what is angiogenesis new blood vessels being formed 3 of 16 why do tumours need blood vessels needed to support tumour growth beyond 1 million cells 4 of 16 difference between normal cell and cancer cell adhesion normal- adhesive and embedded in tissue. cancer - lost adhesiion (cadherin), can travel to other tissues 5 of 16 whats unique about cancer genomes they show abnormalities 6 of 16 what favours tumour progression acquiring the mutator phenotype 7 of 16 how many genes which mutations have implicated in cancer 488 8 of 16 the 2 gene types are oncogenes, tumour supressor 9 of 16 what do tumour supressor genes do inhibit cell proliferation and tumour development 10 of 16 what do oncogenes do drive abnormal cell proliferation, can enter cells as a virus 11 of 16 what is a proto-oncogenes a normal gene which, when altered by mutation, becomes an oncogene 12 of 16 what are the different types of tumour supressors caretakers, gatekeepers, landscapers 13 of 16 function of caretakers promote genome stability & control mutation rate 14 of 16 gatekeepers function monitor cell division and death 15 of 16 landscapers function control the cellular microenvironment 16 of 16
Comments
No comments have yet been made