Which cognitive phenotypes does Williams Beurens Syndrome link to specific genes via double dissociations?
Language, social, spatial cognition
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Which cognitive phenotypes are represented in the DD between WS and SLI?
Language
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Which cognitive phenotypes are represented in the DD between WS and autism?
Social cognition
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Which cognitive phenotypes are represented in the DD between WS and Down syndrome
Space
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Why is there interest in Williams syndrome as a model for developmental disorders?
Because of its well defined genetic pathology
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Does WS show expressive or telegraphic language?
Expressive as opposed to telegraphic in Down syndrome
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What do WS show unusual performance in as measured by word fluency task?
Vocabulary
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How does cognitive genetics explain WS?
The genes coding for language skills are intact, other developmental disorders are impaired on these genes.
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How doesneuroconstructivism explain WS?
The adult state of the language system may be mature but not 'intact'. Language is atypical in many ways, WS informs about the low level processes of language
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What would you expect to see in social interactions from a WS sufferer?
Socially engaging, poor TOM, cant distinguish lies from irony and positive socially inappropriate behaviour
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What does the local-processing bias hypothesis suggest about the nature of WS visual-spatial disorder?
WS have issues with the global form of objects but do not struggle with fine detail
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What is the main premise of the dorsal stream deficit hypothesis?
Structural abnormalities in dorsal stream of WS contribute to visual-spatial deficits
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Typically developing children (at 4-5 years) are worse at?
Worse at motion over form processing
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Do WS children significantly differ from typically developing 4-5 year olds when matched for mental age in motion/form processing?
No
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How does cognitive genetics explain the spatial cognitive deficits in WS?
Genes missing in WS also involved in anatomical development of dorsal stream pathways
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How does neuroconstructivism explain the spatial cognitive deficits in WS?
WS individuals impaired in spatial cognition as dorsal stream develops unusually bc WS individual does not detect visuo-spatial properties
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What does cognitive genetics emphasise?
The role of genes in coding cognitive abilities. Are specific cognitive modules selectively affected?
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What does neuroconstructivism emphasise?
The role of gene expression THROUGH developement. Early cognitive profile inferred from adult end state. Fractionation of strengths and weaknesses across domains,disregard of environment
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Other cards in this set
Card 2
Front
Which cognitive phenotypes are represented in the DD between WS and SLI?
Back
Language
Card 3
Front
Which cognitive phenotypes are represented in the DD between WS and autism?
Back
Card 4
Front
Which cognitive phenotypes are represented in the DD between WS and Down syndrome
Back
Card 5
Front
Why is there interest in Williams syndrome as a model for developmental disorders?
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