A.k.a thrombocytes
Cytoplasmic fragments
no nucleus
membrane bound
Contain granules
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What is haematopoiesis?
The production of RBCs, WBCs and platelets from HSC
Occurs in the bone marrow
Maintains balance between self-renewal, terminal differentiatio, migration and cell death
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What are the sites of haematopoiesis with age?
Fetus: 0-2 mths (yolk sac)
2-7 mths (liver and spleen)
5-9 mths (bone marrow)
In infants - throughout bone marrow
Adulthood: axial skeleton
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What is the overal cellular organisation of haematopoiesis?
Transport (RBCs and Plasma)
Defence (WBCs)
Homeostasis (fibrinogen in clotting)
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What is haemoglobin (Hb)?
Protein tetramer made up of 4 polypeptide chains: 2 alpha globin chains, 2 beta globin chains
Where oxygen binds carrying it from the lungs to the tissues
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Other cards in this set
Card 2
Front
What are some features of red blood cells?
Back
A.k.a Erythrocytes
Biconcave discs
No nucleus and do not contain DNA, RNA or mitochondria
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