Immunology Key Word Revision

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A microorganism that causes disease
pathogen
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The body’s own cells and molecules
self
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Not your own body’s cells and molecules.
Foreign
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A molecule that triggers an immune response by lymphocytes.
Antigen
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Type of white blood cell responsible for the immune response. They become activated in the presence of antigens
Lymphocyte
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Type of white blood cell which carries out a non-specific immune response and ingests and breaks down pathogens by phagocytosis.
Phagocyte
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Mechanism by which phagocytes engulf particles to form a vesicle or a vacuole.
Phagocytosis
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Contain enzymes called lysozymes which they release into the phagosome which hydrolyse the bacterium.
Lysosome
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A vesicle formed as the bacterium is engulfed by the phagocyte.
phagosome
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e.g. phagocyte displays foreign antigens on their own cell-surface membrane
antigen-presentation
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The type of response when T lymphocytes respond to antigens that are presented on a body cell.
cell-mediated immunity
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Cells which mature in the thymus and are associated with cell-mediated immunity.
T-cells
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As the receptor on a helper T cell attaches to the antigen this activates the T cell to divide rapidly by mitosis and form a clone of genetically identical cells
conal selection
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Contain receptors which respond to a single antigen.
helper T-cells
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Kill abnormal cells and body cells that are infected by pathogens by producing a protein called perforin which makes holes in the cell-surface membrane.
cytotoxic T-cells
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The type of response which involves B lymphocytes and antibodies
humoral immunity
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cell produces a specific antibody that responds to one specific antigen
B cell
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When the B cell is activated to divide by mitosis it gives a clone of plasma cells which produce and secrete the specific antibody that exactly fits the antigen on the pathogen’s surface
plasma B cells
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A protein with specific binding sites produced by B cells in response to the presence of appropriate antigen.
Antibody
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memory cells which can respond to future infections by the same pathogen by dividing rapidly and developing into plasma cells that produce antibodies as part of the secondary response.
memory B cells
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Antibodies produced by a single clone of cells
monoclonal antibodies
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Caused by initial response to the antigen which involves the production of antibodies and memory cells.
primary response
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Caused by second exposure to the antigen. Memory cells are responsible for this response – they divide rapidly and develop into plasma cells (which secrete many antibodies quickly) and more memory cells.
secondary response
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Resistance to disease that is acquired from the introduction of antibodies from another individual, rather than an individual’s own immune system
passive immunity
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Resistance to disease resulting from the activities of an individual’s own immune system whereby an antigen induces plasma cells to produce antibodies.
active immunity
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Other cards in this set

Card 2

Front

The body’s own cells and molecules

Back

self

Card 3

Front

Not your own body’s cells and molecules.

Back

Preview of the front of card 3

Card 4

Front

A molecule that triggers an immune response by lymphocytes.

Back

Preview of the front of card 4

Card 5

Front

Type of white blood cell responsible for the immune response. They become activated in the presence of antigens

Back

Preview of the front of card 5
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