genetic definitions 0.0 / 5 ? BiologygeneticsUniversityNone Created by: Rebecca 291991Created on: 09-01-14 12:05 1053972148 Across 1. The process of increasing severity or decreasing age of onset of symptoms from one generation to the next (12) 4. Substitution of one base for another in an exon or gene coding region, such that the amino acid sequence is not modified (6, 8) 5. The occurrence of two or more alleles at a particular locus such that the least common allele is present at a frequency of at least 1% of alleles (12) 8. Having only one copy of a gene of DNA sequence in diploid cells (10) Down 1. Version of a DNA sequence at a particular locus (6) 2. Having two different alleles at a particular locus (12) 3. The presence of a mixture of more than one type of mitochondrial DNA within a cell or individual (12) 7. Point on the chromosome (5) 9. A permanent change in a DNA sequence which is generally but not always associated with a disease (8) 10. mode of inheritance in which a mutation in a gene on the X-chromosome causes the phenotype to be expressed in males who are hemizygous or in females who are homozygous for the mutation (1, 6, 9)
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