g protiens recptors part 2

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  • Created by: anna888
  • Created on: 27-10-22 17:39
Gs protien receptor vs Gi protien receptor alpha subunits in each?
Gs has alpha s subunit- stimulate AC. Gi has alpha i subunits - inhibits AC
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exaple of gs and gi protien?
Gs- beta-adrenorecptor. Gi - alpha 2 adrenoreceptor
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describe Gq protien receptor and action of subunits
contains alphaq11 subunits and activates PLC
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decribe role of PLC
action on membrane and cleaves PIP2 into IP3 and DAG
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decribe IP3 and its action
hydrophillic,travels to ER and releases Ca+2 ions. also promotes influx of Ca+2 from outside cell. Ca+2 influx causes cell response
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describe DAG features and roles
hydrophobic,remains on membrane and reruits PKC and phosphorilates it , this inreases effect of IP3
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describe Ca+2 role
binds to protien CaM, which activates CaMK involved in smooth muscle contraction
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example of Gq reptor
alpha 1 adrenorecptor
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describe vasoconstriction in terms of cell signal pathway, include receptor example
alpha 1 adrenoreptor, Gq-PLC-IP3-Ca+2-CaM-CaMK pathway for muscle contraction,bp increases
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describe vasodilation in terms of cell signal pathway, include receptor example
beta 2 adrenoreceptor via Gs-cAMP-PKA pathway. PKA phospholiates protien which causes bp to decrease
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how many types of metatrophic receptors are there? what class are each
5.M-1,3,5 are Gq stimulatory(ACh activated). M-2,4 are Gi
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Other cards in this set

Card 2

Front

exaple of gs and gi protien?

Back

Gs- beta-adrenorecptor. Gi - alpha 2 adrenoreceptor

Card 3

Front

describe Gq protien receptor and action of subunits

Back

Preview of the front of card 3

Card 4

Front

decribe role of PLC

Back

Preview of the front of card 4

Card 5

Front

decribe IP3 and its action

Back

Preview of the front of card 5
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