immune system 1 0.0 / 5 ? Biologyimmune systemUniversityNone Created by: anna888Created on: 24-11-22 18:22 what are the primary lymphnoid organs? what is there role?what is produced in each bone marrow and thymus. make and mature immune cells. b and t produced in bone marrow. t only mature in thymus 1 of 19 what are the secondary lymphnoid organs?whar is there role? appendix, slpeen, lymphnode, tonsils,adenoids. where immune cells fight pathogens 2 of 19 lymphatic vessle vs lymph nodes? lymphatic vessles transport lymphocytes to nodes when infection occurs. lymph nodes are junctions in vesle where pathogen fights occur 3 of 19 two types of immunity? innate and active 4 of 19 3 features of immdeiate innate immunity? barriers, antimicrobial peptides, complement protiens 5 of 19 3 barrier forms and 3 examples physical- epithleial cells with tight junctions. chemial- low pH. microbilogical- normal flora 6 of 19 name the 4 antimircobial peptides? defensins, histatins, lectins, cathelicidins 7 of 19 decribe the complemnt system protiens acting as opsonins- opsonization where complement protiens bind to microbe o make it more identifiable for phagocytosis 8 of 19 what are the four features of induced innate immunity phagocytosis, ytokines, toll like recptors, nk cells 9 of 19 what cells are involved in phagoytosis, how to u incerase its effciancy? neutrophils, monocytes and macrophages. use opsonins 10 of 19 roles of cytokines?what are they produced by? mediate and regulate innate immunity, stimulate haemaopeisis- more immune cells to infection site- inflammation. produced by macrophages 11 of 19 what 3 ytokines induce inflammation? IL-1, IL-6 and TNF 12 of 19 describe 3 steps of inflammation vasodilation, incerased vasular permability and leukoyte migration 13 of 19 what are TLRs receptors on immune cells or endosomes. surface receptos reognise bacteria. endomal recepors recognise virus 14 of 19 describe TLR action in bacteria bacteria LPS recognised by TLR on macropgae. signal transduction means macrophage activates cyotkines. phagocyosis 15 of 19 describe TLR role in virus viral rna actiate endosmal TLR, leads to production of interferons with antiviral properties 16 of 19 describe anitviral role of interferons induce viral replicaiob resitance, increase nk recptor ligans, activate nk cells to kill the virus 17 of 19 activation of nk cells? how do they work via IFN alpha and beta cytokines. kill ells by inducing apoptosis or use iFN gamma to indirectly kill the cell 18 of 19 important TLRs in bacteria and virus? bacteria- TLR-4. virus TLR-7 19 of 19
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