drug targets

?
  • Created by: anna888
  • Created on: 28-01-23 18:45
3 thoughts behind target identification
are cellular/molecular targets present. is their literature avilable. have assays been developed already
1 of 7
what methodolgies are used to idenitfy targets
genetic and protiens
2 of 7
describe features of a drug target
is in diseased tissue, is over expressed in diseased tissue, has a role in disease progression
3 of 7
what are three drug target concepts
make a drug for a disease, good target bad drug can work, but not other way around. clinical data defines clinical relevance
4 of 7
what is target validation
it nsure a target provides meaningful theraputic outcomes and is safe, it requires pre clincal and clinical tests. it is the most important part of process.
5 of 7
describe important of target selectivity and specificity
increased selectvity reduces unwanted outcomes, it allows very specific drugs for specific diseases and organs
6 of 7
describe systems pharmacology
it involves defining the biological networks perturbed by the disease and the drug action. define risks, mechanisms and toxiclogy so that when a drug fails u can see where u went wrong and process of drug development can be sped up for other drugs
7 of 7

Other cards in this set

Card 2

Front

what methodolgies are used to idenitfy targets

Back

genetic and protiens

Card 3

Front

describe features of a drug target

Back

Preview of the front of card 3

Card 4

Front

what are three drug target concepts

Back

Preview of the front of card 4

Card 5

Front

what is target validation

Back

Preview of the front of card 5
View more cards

Comments

No comments have yet been made

Similar Biology resources:

See all Biology resources »See all drug targets resources »