Calcium regulation & the parathyroid gland

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1. 2 cells of parathyroid gland: chief and oxyphil. which one Appear at puberty
Larger size and smaller nucleus vs chief cells

  • Oxyphil cells
  • Chief cells
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2. name for bone-forming cells
Secrete osteoid (forms bone matrix)
Also begin mineralisation

  • Osteoblasts
  • Osteocytes
  • Osteoclasts

3. what's untrue of HYPERPARATHYROIDISM

  • Calcium homeostatic loss due to excessive PTH secretion
  • Treatment: rehydration, i.v. bisphosphonates, calcitonin (moderate cases), treat underlying cause
  • Treatment: dehydration, i.v. trisphosphonates, calcitonin (moderate cases), treat underlying cause
  • Hypercalcaemia results, from combined excessive effects of:
    PTH-induced bone resorption
    intestinal calcium absorption
    renal tubular reabsorption
  • Due to excess PTH secreted from:
    Benign tumour of one of 4 glands or
    Hyperplasia of all 4 glands

4. effect of PTH on PLASMA PHOSPHATE LEVELS

  • decrease
  • increase

5. name for Osteoclasts
Function in resorption and degradation of existing bone
opposite of osteoblasts
Regulate Ca2+ release from bone

  • Osteoblasts
  • Osteoclasts
  • Osteocytes
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