1. At a PaO2 of 13.3 kPa, approximately how saturated is arterial blood?
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2. How many sub-units make up haemoglobin?
3. Thalassaemia can present in either it's alpha or beta form. Which is more serious, and why?
- Beta form, due to the beta globin chain's presence in adult haemoglobin (HbA)
- Alpha form, due to the alpha globin chain's presence in all haemoglobin types
- Beta form, due to the beta globin chain's presence in all haemoglobin types
- Alpha form, as it's the ruler of the globin empire, and the empire needs a leader
4. What is the approximate oxygen content of normal arterial blood?
- 250 ml/l
- 150 ml/l
- 200 ml/l
- 100 ml/l
5. What is the specific mutation for sickle cell disease?
- Valine for Glutamine at Codon 6
- Glycine for Leucine at Codon 3
- Adenine for Cytosine at Codon 4
- Cytosine for Guanine at Codon 5