Blood Gases and Haemoglobin - BM5 RCR1

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1. Why do sickle cell abnormalities not manifest themselves until approximately 6 months of age?

  • At 6 months, the child learns to stand upright and walk
  • At 6 months, Glycine is switched for Leucine at Codon 3
  • At 6 months, HbA starts to replace HbF
  • At 6 months, there is a large increase in the quantity of erythropoeitin
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Other questions in this quiz

2. At a PaO2 of 13.3 kPa, approximately how saturated is venous blood?

  • 98%
  • 75%
  • 22%
  • 50%

3. What is the specific mutation for sickle cell disease?

  • Valine for Glutamine at Codon 6
  • Adenine for Cytosine at Codon 4
  • Cytosine for Guanine at Codon 5
  • Glycine for Leucine at Codon 3

4. From what week of gestation are embryonic forms of Hb replaced by HbF?

  • Week 14
  • Week 15
  • Week 13
  • Week 12

5. True or false: sickling leads to shortened erythrocyte survival and impaired flow through the microcirculation?

  • True
  • Emmental
  • False
  • Pass

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