1. Why do sickle cell abnormalities not manifest themselves until approximately 6 months of age?
- At 6 months, the child learns to stand upright and walk
- At 6 months, Glycine is switched for Leucine at Codon 3
- At 6 months, HbA starts to replace HbF
- At 6 months, there is a large increase in the quantity of erythropoeitin
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Other questions in this quiz
2. At a PaO2 of 13.3 kPa, approximately how saturated is venous blood?
3. What is the specific mutation for sickle cell disease?
- Valine for Glutamine at Codon 6
- Adenine for Cytosine at Codon 4
- Cytosine for Guanine at Codon 5
- Glycine for Leucine at Codon 3
4. From what week of gestation are embryonic forms of Hb replaced by HbF?
- Week 14
- Week 15
- Week 13
- Week 12
5. True or false: sickling leads to shortened erythrocyte survival and impaired flow through the microcirculation?