The ANS & the Respiratory System - BM5 RCR1

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Which nerve fibres predominantly innervate blood vessels?
Sympathetic
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Contraction of what type of muscle leads to narrowing of the airway lumen & bronchoconstriction?
Smooth muscle
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What type of innervation does bronchial smooth muscle have?
Parasympathetic
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When circulating adrenaline comes into contact with beta adrenoceptors on the bronchial smooth muscle, what action does this cause?
Relaxation
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Other than beta agonists, what other drug type relaxes bronchial smooth muscle?
Muscarinic Antagonists
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Other than bronchodilation, what other effect do muscarinic antagonists have?
Reduce secretions (e.g. mucus)
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The action of adrenalin on which receptor causes increased renin secretion in the kidney?
Beta II
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The action of adrenalin on which receptor causes glycogenolysis in the liver?
Alpha & Beta II
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The action of adrenalin on which receptor causes decreased GI motility?
Alpha & Beta II
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What is status asthmaticus?
An acute severe asthma attack
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Which drug is used to treat status asthmaticus in individuals with healthy hearts?
Adrenaline
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Which drug is used to treat acute anaphylaxis?
Adrenaline
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You come across a member of the public having an acute anaphylactic episode. Having administered an EpiPen injection of adrenalin, why is important to get them to hospital as soon as possible?
Adrenalin is metabolised quickly and will only last for 30mins, they need to get to a hospital for further treatment
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Which selective beta II antagonist is most commonly used to treat mild asthma symptoms?
Salbutamol
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True or false: Beta II agonists treat the underlying causes of airway inflammation?
False
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True or false: Overuse of salbutamol can down-regulate beta adrenoceptors expression, reducing the effectiveness of salbutamol?
True
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What is the duration of action of salmeterol?
12hrs
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With what can salmeterol be combined to reduce airway inflammation?
Steroid
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For what reason should beta blockers not be given to asthmatics?
Beta blockers antagonise beta agonists and cause severe bronchoconstriction
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What is the duration of action of muscarinic antagonists used for treating asthma?
4-6hrs
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What are the expected side effects of muscarinic antagonists?
Constipation (+ tachycardia & AF)
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Other cards in this set

Card 2

Front

Contraction of what type of muscle leads to narrowing of the airway lumen & bronchoconstriction?

Back

Smooth muscle

Card 3

Front

What type of innervation does bronchial smooth muscle have?

Back

Preview of the front of card 3

Card 4

Front

When circulating adrenaline comes into contact with beta adrenoceptors on the bronchial smooth muscle, what action does this cause?

Back

Preview of the front of card 4

Card 5

Front

Other than beta agonists, what other drug type relaxes bronchial smooth muscle?

Back

Preview of the front of card 5
View more cards

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