Either; too much dopamine or the receptors are too sensitive
1 of 5
Support Dopamine Hypothesis
L-Dopa = Phenothiazine - Speeds up dopamine, LSD & Amphetamines = Give Sz symptoms - They increase the amount of dopamine
2 of 5
Ranrup & Munkvad
Gave rats amphetamines (activate dopamine production) - creating Sz-like symptoms - Gave them neuroleptic drugs (inhibit release of dopamine) - Reversed the effects
3 of 5
Iversen
Reported that post mortems on people who were Sz had excess dopamine in the limbic system - Suggesting dopamine is involved in the disorder
4 of 5
Kesler et al
Used MRI and PET scans to compare Sz and non-Sz patients - They found differences in dopamine levels - Suggesting dopamine is important in the onset of Sz
5 of 5
Other cards in this set
Card 2
Front
L-Dopa = Phenothiazine - Speeds up dopamine, LSD & Amphetamines = Give Sz symptoms - They increase the amount of dopamine
Back
Support Dopamine Hypothesis
Card 3
Front
Gave rats amphetamines (activate dopamine production) - creating Sz-like symptoms - Gave them neuroleptic drugs (inhibit release of dopamine) - Reversed the effects
Back
Card 4
Front
Reported that post mortems on people who were Sz had excess dopamine in the limbic system - Suggesting dopamine is involved in the disorder
Back
Card 5
Front
Used MRI and PET scans to compare Sz and non-Sz patients - They found differences in dopamine levels - Suggesting dopamine is important in the onset of Sz
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