Lecture 16- Physiological Aspects of the Endocrine System

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  • Created by: julieo
  • Created on: 10-01-16 13:59

What is a hormone?

  • A chemical sign that enables an event in one part of the body to have an effect elsewhere in the body

Thyroid gland

  • Secretes T3 and T4 follicular cells
  • Calcitonin - parafollicular cells

3 Types of cell signalling

  • Autocrine
  • Paracrine
  • Endocrine

Proteins, peptides and amines

  • Hydrophilic
  • Cell surface receptors, act via second messenger systems
  • Circulate primarily dissolved in plasma

Steroids and Thyroid hormones

  • Hydrophobic
  • Intracellular receptors, promote or supress gene transcription
  • Circulate primarily bound to plasma proteins

Factors

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