(3) Enzyme-substrate specificity and activity
- Created by: Tanya Phillips
- Created on: 29-03-13 10:02
Explain Enzyme-Substrate specificity
Enzymes make it easier for a reaction to take place.
A substrate is a molecule upon which an enzyme acts. It binds to a specific area of an enzyme called the active site.
The substrate fits into the active site of the enzyme as a key fits into a lock. This is called the lock and key model of enzyme action. Shown below.
The 3 dimensional structure of a protein (ENZYME IS A PROTEIN) determines the shape of the active site. The substrate fits into the active site and reaction proceeds.
If a molecule has the "wrong" shape it cannot fit into the active site and will not react.
Therefore an enzyme only works with a specific substrate and only catalyzes a specific reaction.
Enzyme specificity is due to the complementary shape of the active site and…
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