Enzyme Inhibition

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Competitive Inhibition

  • inhibitor is structurally similar to the substrate and competes with the active site of the enzymes (has a shape that lets it fit into the active site of the enzyme in place of the substrate
  • Example - malonic acid competes with succinate for the active sites of succinic dehydrogenase, an important enzyme in the Krebs cycle in respiration
  • if substrate concentration is increase it will reduce…


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