Enzyme Inhibition

Competitive Inhibition

• inhibitor is structurally similar to the substrate and competes with the active site of the enzymes (has a shape that lets it fit into the active site of the enzyme in place of the substrate
• Example - malonic acid competes with succinate for the active sites of succinic dehydrogenase, an important enzyme in the Krebs cycle in respiration
• if substrate concentration is increase it will reduce…