Lipids - Complete Summary

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General Characteristics

  • made of carbon, hydrogen and oxygen
  • they have a very high carbon-hydrogen to oxygen ratio
  • they have a low mass to high energy ratio
  • they are insolube in water
  • they are soluble in organic solvents
  • they are osmotically inactive
  • fatty acids (represented by RCOOH)
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Functions

  • source of energy
  • insulation of heat and electrical impulses (myelin sheaths)
  • waterproofing (oily secretion from skin)
  • protection of organs
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Triglycerides

  • ester bond between each fatty acids and the glycerol molecule
  • esterification (condensation reactions) result in ester bond formation
  • emulsification (hydroylsis reactions) result in monoglyceride and fatty acid formation
  • glycerol formula is C3H8O3
  • glycerol is an alcohol (OH group)
  • fatty acids can be
    • saturated (CnH2n+1)(COOH)
    • monounsaturated (CnH2n-1)(COOH)
    • polyunsaturated (CnH2n-1-1...)
  • OH of COOH and H of OH (glycerol) form H20
  • non-polar
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Phospholipids

  • glycerol and 2 fatty acids
  • insoluble - hydrophobic head
  • phosphate group is soluble (polar) - hydrophilic head
  • phosphate group is (PO4^3-)
  • form bilayer for membrane or surfactants on water
  • form glycolipids with carbohydrates in membrane
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Test of Lipids

  • 2cm3 of sample
  • 5cm3 of ethanol
  • shake to dissolve
  • 5cm3 water
  • cloudy-white colour = lipid presence
  • emulsion formation
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Digestion

  • live produces bile salts
  • break down lipids into micelle droplets by emulsification of ester bonds
  • pancreas makes pancreatic juices
  • pancreatic juice contains lipases
  • breaks down ester bonds of micelle droplets
  • into monoglycerise and fatty acids
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Absorption

  • micelle droplets remained associated with bile salts until they reach the villi of the ileum
  • come into contact with villi
  • micelles break down into monoglycerides and fatty acids with lipase
  • enter the epithelial cells andreach endoplasmic reticulum
  • reformed into triglycerides
  • move to golgi body
  • associate with cholesterol and lipoproteins to form chylomicrons
  • leave epithelial cell by exocytosis
  • enter lacteals
  • break down into triglycerides in the blood vessels
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