Hormones in Reproduction

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  • Created by: ssavage
  • Created on: 01-03-16 19:06
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  • Reproductive Hormones
    • LH
      • Lutenising hormone triggers the release of an oocyte from a follicle in women. In men, it binds to receptors on Leydig cells in testes to stimulate secretion of testosterone.
    • FSH
      • Follicle Stimulating Hormone stimulates the development of follicles in women by binding to them, and binds to Sertoli cells in mean making them more receptive to testosterone.
    • Oestrogen
      • During pregnancy, these hormones cause breast tissue to develop in readiness for lactation. Inhibits oxytocin until just before birth.
        • Progesterone
      • Released by mature follicles to inhibit LH and FSH, but then causes the LH surge and the release of an oocyte.
    • Testosterone
      • Affects Sertoli cells to trigger spermatogenesis, and acts to inhibit LH when levels are high.
    • Progesterone
    • HCG
      • Human Chorionic Gonadotrophin stimulates the corpus luteum to release progesterone and oestrogen during pregnancy to maintain lining of the uterus and ensure implantation of a blastocyst
    • HPL
      • Human Placental Lactogen ensures breast tissue is receptive to oestrogen and progesterone. Also maintains maternal blood glucose levels.
    • Oxytocin
      • Coincides with falling levels of progesterone to stimulate contraction of uterine muscles during birth, and activates muscles surrounding milk glands during lactation.
    • Prolactin
      • Prolactin maintains milk production in breast tissue during lactation and prevents ovulation.
    • GnRH
      • Gonadotrophin releasing hormone is secretes by the hypothalamus and binds to receptors on the anterior pituitary gland to stimulate the synthesis and release on FSH and LH
    • Inhibin
      • Secreted by the granulosa cells in women and the Sertoli cells in men, inhibin acts to inhibit FSH as a form of negative feedback
  • Male
  • Female
  • Both


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