Antibiotics, Disinfectants & Antiseptics

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  • Created by: Jenny1809
  • Created on: 08-06-17 11:50
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  • Prevent Infection
    • Antiseptics
      • Apply: skin or wounds
      • Kill bacteria in localised area
      • Reduce likelihood: wound infected or bacteria entering blood
    • Disinfectants
      • Kill bacteria in localised area
      • Reduce likelihood: bacteria transferred from environment to patient/wound
      • Apply: inanimate objects & surface
    • Antibiotics
      • Reduce likelihood: Passing on infection by direct or indirect contact
        • Slow bacterial cell growth & reproduction
          • Fewer cells produced
            • More time for immune system to respond
              • Clonal expansion of B cells
              • Antibody production
                • Clonal expansion of B cells
              • Phagocytosis
      • = antibacterial drugs (kill / prevent bacteria reproduction)
        • Broad spectrum: destroy wide range bacteria & pathogen, (including good/neutral flora)
        • Bactericidal: destroys pathogens present
        • Bacteriostatic: Inhibits the growth of the microorganism
      • Selective Toxicity: interfere with metabolism & function of pathogen with minimum damage to human host
        • Inhibit bacterial cell wall synthesis
          • Cell lysis
        • Disrupt cell membrane - changing it's permeability
          • Cell lysis
        • Inhibit nucleic acid synthesis, replication & transcription
        • Inhibit protein synthesis

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