monoclonal antibodies
- Created by: JTre
- Created on: 27-03-19 22:39
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- Monoclonal Antibodies
- clone
- a clone is an exact copy/replica of something
- antibody
- an antibody is a protein produced by the immune system that attacks antigens.
- work in lock and key
- similar to enzymes
- Produced by a type of white blood cell called lymphocytes
- Hybridoma
- The name given to the cells formed when a spleen cell is fused with a myeloma cell
- produces the monoclonal antibodies
- pregnancy tests
- The hormone HCG is only produced during pregnancy
- Monoclonal antibodies are located on the test zone of the pregnancy test
- When HCG is present in the woman's urine, the antibodies will bind to the HCG and produce a colour change
- This is how a pregnancy test can determine whether a woman is pregnant or not
- how they're made
- 1. an antigen is injected into the mouse
- 2, mouse produces lymphocytes to fight antigen
- 3. lymphocytes are removed from mouse
- 4. lymphocytes are fused with myeloma cells to form hybridoma cells
- 5. hybridoma cells undergo mitosis and thus create the monoclonal antibodies specific to the original antigen
- IDENTICAL COPIES OF ONE TYPE OF ANTIBODY
- clone
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