monoclonal antibodies

  • Created by: JTre
  • Created on: 27-03-19 22:39
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  • Monoclonal Antibodies
    • clone
      • a clone is an exact copy/replica of something
    • antibody
      • an antibody is a protein produced by the immune system that attacks antigens.
      • work in lock and key
        • similar to enzymes
      • Produced by a type of white blood cell called lymphocytes
    • Hybridoma
      • The name given to the cells formed when a spleen cell is fused with a myeloma cell
      • produces the monoclonal antibodies
    • pregnancy tests
      • The hormone HCG is only produced during pregnancy
      • Monoclonal antibodies are located on the test zone of the pregnancy test
      • When HCG is present in the woman's urine, the antibodies will bind to the HCG and produce a colour change
      • This is how a pregnancy test can determine whether a woman is pregnant or not
    • how they're made
      • 1. an antigen is injected into the mouse
      • 2, mouse produces lymphocytes to fight antigen
      • 3. lymphocytes are removed from mouse
      • 4. lymphocytes are fused with myeloma cells to form hybridoma cells
      • 5. hybridoma cells undergo mitosis and thus create the monoclonal antibodies specific to the original antigen
    • IDENTICAL COPIES OF ONE TYPE OF ANTIBODY

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