Issues Relating to Genetic Manipulation

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  • Issues Relating to Genetic Manipulation
    • Microorganism e.g. E. coli
      • Produce Human Insulin to treat Diabetes
      • Produce HGH to treat pituitary dwarfism
      • May transfer antibiotic resistance to wild bacteria
        • HOWEVER - GM bacteria require an essential nutrient and do not survive long outside the lab
    • Plants: Bt tobacco and Bt maize
      • Bt plants produce their own pesticide which eliminates the need to spray crops
      • Bt toxic to monarch butterflies
        • HOWEVER, monarch butterflies don't feed off tobacco or maize nectar anyway so continue to thrive
    • Plants: Soya Beans
      • Herbicide Resistant: Weeds surrounding crops can be killed without harming crop
      • Potential for herbicide resistance to be passed on creating 'superweeds'.
    • Golden Rice
      • GM rice contains Beta Carotene (the precursor for Vit A) to prevent child blindness in third world countries
      • Farmers may have to buy the seeds every year
        • HOWEVER: the company that developed golden rice has offered free licences to farmers to keep and replant seeds
    • Plantains
      • Nutritionally enhanced (enzyme cofactor used for regulating insulin)
      • People fear eating food containing foreign DNA will cause traits to be expressed in us
        • HOWEVER: all food we eat contains DNA and it is digested using enzymes, nucleases and nuleotidases
    • Crop Plants
      • GM to be pest resistant to prevent farmers needing to spray pesicides
      • Concerns raised as to giving the farmers the choice which crop seeds to buy
    • Pathogens
      • GM viruses have no virulence to reduce the chance of vaccine recipients becoming ill
      • Allele may be inserted into the genome in a way that increases risk of cancer or interferes with gene regulation
    • Mice
      • GM mice bred for medical research and testing into the function of certain genes and the development of breast cancer therapies
      • Animal testing objections
        • HOWEVER: Strict animal welfare regulations and benefits for human health
    • Pharmaceutical Proteins
      • Human pharmaceutical proteins (e.g. alpha antitrypsin to treat emphysema) can be inserted into goats and sheep and the human protein harvested from their milk
      • Welfare concerns of GM sheep and goats
        • HOWEVER: Strict animal welfare regulations and benefits for human health
    • Silk
      • GM goats produce silk due to spider gene inserted into their genome. Silk is used for cables, sutures, artificial ligaments and bullet proof vests
      • Welfare concerns of GM sheep and goats

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